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Stabilization of the ADP/Metaphosphate Intermediate during ATP Hydrolysis in Pre-power Stroke Myosin: QUANTITATIVE ANATOMY OF AN ENZYME
It has been proposed recently that ATP hydrolysis in ATPase enzymes proceeds via an initial intermediate in which the dissociated γ-phosphate of ATP is bound in the protein as a metaphosphate (P(γ)O(3)(−)). A combined quantum/classical analysis of this dissociated nucleotide state inside myosin prov...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853302/ https://ncbi.nlm.nih.gov/pubmed/24165121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.500298 |
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