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Chronic Increase of Urea Leads to Carbamylated Proteins Accumulation in Tissues in a Mouse Model of CKD

Carbamylation is a general process involved in protein molecular ageing due to the nonenzymatic binding of isocyanic acid, mainly generated by urea dissociation, to free amino groups. In vitro experiments and clinical studies have suggested the potential involvement of carbamylated proteins (CPs) in...

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מידע ביבליוגרפי
Main Authors: Pietrement, Christine, Gorisse, Laëtitia, Jaisson, Stéphane, Gillery, Philippe
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853192/
https://ncbi.nlm.nih.gov/pubmed/24324801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082506
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