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Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the pro-inflammatory cytokines IL-6 and IL-8

Triple-negative breast cancers (TNBCs) are aggressive with no effective targeted therapies. A combined database analysis identified 32 inflammation-related genes differentially expressed in TNBCs, 10 proved critical for anchorage-independent growth. In TNBC cells a LPA-LPAR2-EZH2 NF-kappaB signaling...

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Detalhes bibliográficos
Main Authors: Hartman, Zachary C., Poage, Graham M., den Hollander, Petra, Tsimelzon, Anna, Hill, Jamal, Panupinthu, Nattapon, Zhang, Yun, Mazumdar, Abhijit, Hilsenbeck, Susan G., Mills, Gordon B., Brown, Powel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853111/
https://ncbi.nlm.nih.gov/pubmed/23633491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4524-T
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