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Differential PKA activation and AKAP association determines cell fate in cancer cells
BACKGROUND: The dependence of malignant properties of colorectal cancer (CRC) cells on IGF1R signaling has been demonstrated and several IGF1R antagonists are currently in clinical trials. Recently, we identified a novel pathway in which cAMP independent PKA activation by TGFβ signaling resulted in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853032/ https://ncbi.nlm.nih.gov/pubmed/24083380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-8-10 |
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