An Immunomodulating Fatty Acid Analogue Targeting Mitochondria Exerts Anti-Atherosclerotic Effect beyond Plasma Cholesterol-Lowering Activity in apoE(-/-) Mice

Tetradecylthioacetic acid (TTA) is a hypolipidemic antioxidant with immunomodulating properties involving activation of peroxisome proliferator-activated receptors (PPARs) and proliferation of mitochondria. This study aimed to penetrate the effect of TTA on the development of atherosclerotic lesions...

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Detalhes bibliográficos
Main Authors: Vik, Rita, Busnelli, Marco, Parolini, Cinzia, Bjørndal, Bodil, Holm, Sverre, Bohov, Pavol, Halvorsen, Bente, Brattelid, Trond, Manzini, Stefano, Ganzetti, Giulia S., Dellera, Federica, Nygård, Ottar K., Aukrust, Pål, Sirtori, Cesare R., Chiesa, Giulia, Berge, Rolf K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852987/
https://ncbi.nlm.nih.gov/pubmed/24324736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081963
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