Collagen Binding Provides a Sensitive Screen for Variant Von Willebrand Disease

BACKGROUND: Von Willebrand factor (VWF) is a multimeric protein that binds platelets and collagen, facilitating hemostasis at sites of vessel injury. Measurement of VWF multimer distribution is critical for diagnosis of variant von Willebrand disease (VWD), particularly types 2A and 2B, but the typi...

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Bibliografiske detaljer
Main Authors: Flood, Veronica H., Gill, Joan Cox, Friedman, Kenneth D., Christopherson, Pamela A., Jacobi, Paula M., Hoffmann, Raymond G., Montgomery, Robert R., Haberichter, Sandra L.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852672/
https://ncbi.nlm.nih.gov/pubmed/23340442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2012.199000
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