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Evaluation of the effect of genetic variation on the relationship between statins, cardiovascular disease and cancer

Statins are a class of medications that are competitive inhibitors of Hydroxy Methyl Glutaryl Co-enzyme A (HMG-CoA) reductase which is the rate-limiting enzyme in the cholesterol bio-synthesis pathway. As a result, statins lower total cholesterol and low density lipoprotein (LDL) cholesterol thus im...

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Hlavní autoři: Desai, Pinkal, Jay, Allison, Bock, Cathryn, Dyson, Gregory, Okwuosa, Tochukwu, Simon, Michael S
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852638/
https://ncbi.nlm.nih.gov/pubmed/24319534
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