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Dual Inhibiting Senescence and Epithelial-to-Mesenchymal Transition by Erythropoietin Preserve Tubular Epithelial Cell Regeneration and Ameliorate Renal Fibrosis in Unilateral Ureteral Obstruction

This study aims to investigate the renoprotective effect of recombinant human erythropoietin (rhEPO) treatment could preserve tubular epithelial cell regeneration and ameliorate renal fibrosis by dual inhibition of stress-induced senescence and EMT in unilateral ureteric obstruction (UUO) mouse mode...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tasanarong, Adis, Kongkham, Supranee, Khositseth, Sookkasem
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852581/
https://ncbi.nlm.nih.gov/pubmed/24350257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/308130
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