Mycobacterium tuberculosis Specific CD8(+) T Cells Rapidly Decline with Antituberculosis Treatment

RATIONALE: Biomarkers associated with response to therapy in tuberculosis could have broad clinical utility. We postulated that the frequency of Mycobacterium tuberculosis (Mtb) specific CD8(+) T cells, by virtue of detecting intracellular infection, could be a surrogate marker of response to therap...

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Autors principals: Nyendak, Melissa R., Park, Byung, Null, Megan D., Baseke, Joy, Swarbrick, Gwendolyn, Mayanja-Kizza, Harriet, Nsereko, Mary, Johnson, Denise F., Gitta, Phineas, Okwera, Alphonse, Goldberg, Stefan, Bozeman, Lorna, Johnson, John L., Boom, W. Henry, Lewinsohn, Deborah A., Lewinsohn, David M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852504/
https://ncbi.nlm.nih.gov/pubmed/24324704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081564
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