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Poly-L-glutamate/glutamine synthesis in the cell wall of Mycobacterium bovis is regulated in response to nitrogen availability

BACKGROUND: The cell wall of pathogenic mycobacteria is known to possess poly-L-glutamine (PLG) layer. PLG synthesis has been directly linked to glutamine synthetase (GS) enzyme. glnA1 gene encodes for GS enzyme in mycobacteria. PLG layer is absent in cell wall of avirulent Mycobacterium smegmatis,...

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Autori principali: Tripathi, Deeksha, Chandra, Harish, Bhatnagar, Rakesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852478/
https://ncbi.nlm.nih.gov/pubmed/24112767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-13-226
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