Non-invasive measurement of cerebral oxygen metabolism in the mouse brain by ultra-high field (17)O MR spectroscopy

To assess cerebral energetics in transgenic mouse models of neurologic disease, a robust, efficient, and practical method for quantification of cerebral oxygen consumption is needed. (17)O magnetic resonance spectroscopy (MRS) has been validated to measure cerebral metabolic rate of oxygen (CMRO(2))...

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Bibliographic Details
Main Authors: Cui, Weina, Zhu, Xiao-Hong, Vollmers, Manda L, Colonna, Emily T, Adriany, Gregor, Tramm, Brandon, Dubinsky, Janet M, Öz, Gülin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Brief Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851910/
https://ncbi.nlm.nih.gov/pubmed/24064490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.172
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