Genetic and biochemical markers of hydroxyurea therapeutic response in sickle cell anemia

BACKGROUND: Sickle cell anemia (SCA) presents a complex pathophysiology which can be affected by a number of modifying factors, including genetic and biochemical ones. In Brazil, there have been no studies verifying β(S)-haplotypes effect on oxidative stress parameters. This study evaluated β(S)-hap...

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Autori principali: Silva, Danilo Grunig Humberto, Belini Junior, Edis, Carrocini, Gisele Cristine de Souza, Torres, Lidiane de Souza, Ricci Júnior, Octávio, Lobo, Clarisse Lopes de Castro, Bonini-Domingos, Claudia Regina, de Almeida, Eduardo Alves
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851873/
https://ncbi.nlm.nih.gov/pubmed/24106994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-108
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