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Sorting genomes with rearrangements and segmental duplications through trajectory graphs

We study the problem of sorting genomes under an evolutionary model that includes genomic rearrangements and segmental duplications. We propose an iterative algorithm to improve any initial evolutionary trajectory between two genomes in terms of parsimony. Our algorithm is based on a new graphical m...

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Main Authors: Shao, Mingfu, Lin, Yu, Moret, Bernard
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851842/
https://ncbi.nlm.nih.gov/pubmed/24564345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S15-S9
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