Collagen Advanced Glycation Inhibits Its Discoidin Domain Receptor 2 (DDR2)-Mediated Induction of Lysyl Oxidase in Osteoblasts

Diabetes increases the risk of bone fracture. Organic and inorganic bone extracellular matrix components determine bone strength. Previous studies indicate that in diabetes, glycation of collagen causes abnormal arrangements of collagen molecules and fragile bones. Diabetic bone fragility is additio...

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Main Authors: Khosravi, Roozbeh, Sodek, Katharine L., Faibish, Michael, Trackman, Philip C.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851576/
https://ncbi.nlm.nih.gov/pubmed/24120383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.10.001
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