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VprBP Has Intrinsic Kinase Activity Targeting Histone H2A and Represses Gene Transcription

Histone modifications play important roles in the regulation of gene expression and chromatin organization. VprBP has been implicated in transcriptionally silent chromatin formation and cell cycle regulation, but the molecular basis underlying such effects remains unclear. Here we report that VprBP...

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Detalhes bibliográficos
Main Authors: Kim, Kyunghwan, Kim, Jin-Man, Kim, Joong-Sun, Choi, Jongkyu, Lee, Yong Suk, Neamati, Nouri, Song, Jin Sook, Heo, Kyu, An, Woojin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851289/
https://ncbi.nlm.nih.gov/pubmed/24140421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.09.017
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