Cloning and expression of an anti-LDL(-) single-chain variable fragment, and its inhibitory effect on experimental atherosclerosis

The in vivo modified forms of low-density lipoprotein (LDL) are important for the formation of foam cells and as mediators of the immuno-inflammatory process involved in the progression of atherosclerosis. Electronegative LDL, LDL(-), is a LDL subfraction with pro-inflammatory properties that is pre...

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Autori principali: Kazuma, Soraya M, Cavalcante, Marcela F, Telles, Andréia ER, Maranhão, Andrea Queiroz, Abdalla, Dulcineia SP
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851228/
https://ncbi.nlm.nih.gov/pubmed/23924793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.25859
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