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Upward Bias in Estimation of Genetic Effects
Because of the large number of tests for linkage that are performed in genome scans, the naive estimator of the size of a genetic effect in cases of borderline significance can be inflated and lead to unrealistic expectations for successful replication. As a remedy, this report proposes lower confid...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Human Genetics
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC385094/ https://ncbi.nlm.nih.gov/pubmed/12386837 |
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