Irreversibility of cellular aging and neoplastic transformation: a clonal analysis.
Prolonged incubation of NIH 3T3 cells under the growth constraint of confluence results in a persistent impairment of proliferation when the cells are subcultured at low density and a greatly increased probability of neoplastic transformation in assays for transformation. These properties, along wit...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9793 |
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