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Using PPI network autocorrelation in hierarchical multi-label classification trees for gene function prediction

BACKGROUND: Ontologies and catalogs of gene functions, such as the Gene Ontology (GO) and MIPS-FUN, assume that functional classes are organized hierarchically, that is, general functions include more specific ones. This has recently motivated the development of several machine learning algorithms f...

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Autors principals: Stojanova, Daniela, Ceci, Michelangelo, Malerba, Donato, Dzeroski, Saso
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850549/
https://ncbi.nlm.nih.gov/pubmed/24070402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-285
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