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Comparable Molecular Alterations in 4-Nitroquinoline 1-Oxide-induced Oral and Esophageal Cancer in Mice and in Human Esophageal Cancer, Associated with Poor Prognosis of Patients

BACKGROUND: The murine model of 4-nitroquinoline 1-oxide (4-NQO)-induced oral and esophageal cancer is frequently used to assess the effects of different cancer prevention/therapy agents in vivo, but the molecular mechanisms in those 4-NQO-induced carcinogenesis are unknown. This study investigated...

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Detalhes bibliográficos
Main Authors: YANG, ZHENGDUO, GUAN, BAOXIANG, MEN, TAOYAN, FUJIMOTO, JUNYA, XU, XIAOCHUN
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849809/
https://ncbi.nlm.nih.gov/pubmed/23812217
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