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Skewed X-Chromosome Inactivation Is a Common Feature of X-Linked Mental Retardation Disorders

Some deleterious X-linked mutations may result in a growth disadvantage for those cells in which the mutation, when on the active X chromosome, affects cell proliferation or viability. To explore the relationship between skewed X-chromosome inactivation and X-linked mental retardation (XLMR) disorde...

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Udgivet i:Am J Hum Genet
Principais autores: Plenge, Robert M., Stevenson, Roger A., Lubs, Herbert A., Schwartz, Charles E., Willard, Huntington F.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2002
Fag:
Report
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384975/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12068376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1086/341123
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