A Second Locus for Very-Late-Onset Alzheimer Disease: A Genome Scan Reveals Linkage to 20p and Epistasis between 20p and the Amyloid Precursor Protein Region

We used a covariate-based linkage method to reanalyze genome scan data from affected sibships collected by the Alzheimer Disease (AD) Genetics Initiative of the National Institute of Mental Health. As reported in an earlier article, the amyloid-β precursor protein (APP) region is strongly linked to...

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Hauptverfasser: Olson, Jane M., Goddard, Katrina A. B., Dudek, Doreen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC384972/
https://ncbi.nlm.nih.gov/pubmed/12016588
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