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Enantioselective synthesis of (10S)- and (10R)-methyl-anandamides
For the development of novel endocannabinoid templates with potential resistance to hydrolytic and oxidative metabolism, we are targeting the bis-allylic carbons of the arachidonoyl skeleton. Toward this end, we recently disclosed the synthesis and preliminary biological data for the (13S)-methyl-an...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849710/ https://ncbi.nlm.nih.gov/pubmed/24319298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2012.05.010 |
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