Increased AKT or MEK1/2 Activity Influences Progesterone Receptor Levels and Localization in Endometriosis

CONTEXT: Endometriosis is characterized by progesterone resistance and hyperactivity of the AKT and MAPK pathways. Kinases can cause posttranslational modifications of the progesterone receptor (PR) to influence cellular localization and protein stability. OBJECTIVE: The objective of this study was...

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Hauptverfasser: Eaton, Jennifer L., Unno, Kenji, Caraveo, Marshall, Lu, Zhenxiao, Kim, J. Julie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2013
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Hot Topics in Translational Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849681/
https://ncbi.nlm.nih.gov/pubmed/24064688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1661
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