Amyloid-β oligomers regulate the properties of human neural stem cells through GSK-3β signaling

Alzheimer's disease (AD) is the most common cause of age-related dementia. The neuropathological hallmarks of AD include extracellular deposition of amyloid-β peptides and neurofibrillary tangles that lead to intracellular hyperphosphorylated tau in the brain. Soluble amyloid-β oligomers are th...

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Bibliografiske detaljer
Main Authors: Lee, Il-Shin, Jung, Kwangsoo, Kim, Il-Sun, Park, Kook In
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849574/
https://ncbi.nlm.nih.gov/pubmed/24232259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.125
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