PPARγ modulates vascular smooth muscle cell phenotype via a protein kinase G-dependent pathway and reduces neointimal hyperplasia after vascular injury

Vascular smooth muscle cells (VSMCs) undergo phenotypic changes in response to vascular injury such as angioplasty. Protein kinase G (PKG) has an important role in the process of VSMC phenotype switching. In this study, we examined whether rosiglitazone, a peroxisome proliferator-activated receptor...

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Detalhes bibliográficos
Main Authors: Yang, Han-Mo, Kim, Baek-Kyung, Kim, Ju-Young, Kwon, Yoo-Wook, Jin, Sooryeonhwa, Lee, Joo-Eun, Cho, Hyun-Jai, Lee, Hae-Young, Kang, Hyun-Jae, Oh, Byung-Hee, Park, Young-Bae, Kim, Hyo-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849568/
https://ncbi.nlm.nih.gov/pubmed/24287871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.112
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