A Polymorphism in the Agouti Signaling Protein Gene Is Associated with Human Pigmentation

In mice and humans, binding of α-melanocyte–stimulating hormone to the melanocyte-stimulating–hormone receptor (MSHR), the protein product of melanocortin-1 receptor (MC1R) gene, leads to the synthesis of eumelanin. In the mouse, ligation of MSHR by agouti signaling protein (ASP) results in the prod...

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Hlavní autoři: Kanetsky, Peter A., Swoyer, Jennifer, Panossian, Saarene, Holmes, Robin, Guerry, DuPont, Rebbeck, Timothy R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC384954/
https://ncbi.nlm.nih.gov/pubmed/11833005
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