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Testing for Genetic Linkage in Families by a Variance-Components Approach in the Presence of Genomic Imprinting

Some genes that affect development and behavior in mammals are known to be imprinted; and ⩾1% of all mammalian genes are imprinted. Hence, incorporating an imprinting parameter into linkage analysis may increase the power to detect linkage for these traits. Here we propose theoretical justifications...

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Bibliografske podrobnosti
Main Authors: Shete, Sanjay, Amos, Christopher I.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC384951/
https://ncbi.nlm.nih.gov/pubmed/11836650
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