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An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells

We show that cerebral endothelial cells secrete trophic factors that support the survival and proliferation of rat oligodendrocyte precursor cells (OPCs). This OPC-supportive phenomenon was mediated by Akt and Src signaling pathways. Noncytotoxic levels of oxidative stress downregulate trophic facto...

詳細記述

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書誌詳細
主要な著者: Arai, Ken, Lo, Eng H.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849498/
https://ncbi.nlm.nih.gov/pubmed/19357263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0035-09.2009
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