Ursodeoxycholic Acid but Not Tauroursodeoxycholic Acid Inhibits Proliferation and Differentiation of Human Subcutaneous Adipocytes

Stress of endoplasmic reticulum (ERS) is one of the molecular triggers of adipocyte dysfunction and chronic low inflammation accompanying obesity. ERS can be alleviated by chemical chaperones from the family of bile acids (BAs). Thus, two BAs currently used to treat cholestasis, ursodeoxycholic and...

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Hauptverfasser: Mališová, Lucia, Kováčová, Zuzana, Koc, Michal, Kračmerová, Jana, Štich, Vladimír, Rossmeislová, Lenka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849437/
https://ncbi.nlm.nih.gov/pubmed/24312631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082086
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