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Epigenetic Alterations of H19 and LIT1 Distinguish Patients with Beckwith-Wiedemann Syndrome with Cancer and Birth Defects

Beckwith-Wiedemann syndrome (BWS) is a congenital cancer-predisposition syndrome associated with embryonal cancers, macroglossia, macrosomia, ear pits or ear creases, and midline abdominal-wall defects. The most common constitutional abnormalities in BWS are epigenetic, involving abnormal methylatio...

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Detalhes bibliográficos
Main Authors: DeBaun, Michael R., Niemitz, Emily L., McNeil, D. Elizabeth, Brandenburg, Sheri A., Lee, Maxwell P., Feinberg, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384940/
https://ncbi.nlm.nih.gov/pubmed/11813134
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