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The potential contribution of ranolazine to Torsade de Pointe

Ranolazine is a novel anti-anginal agent acting through pharmacologic mechanism of inhibition of the late phase of the inward sodium current. In addition, it is a potent inhibitor of rapid delayed rectifier potassium currents, leading to prolongation of the QT interval. However, ranolazine has not y...

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Hlavní autoři: Liu, Zhigang, Williams, Richard B., Rosen, Boaz D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849286/
https://ncbi.nlm.nih.gov/pubmed/24396259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcdr.2013.08.005
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