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RhoC Interacts with Integrin α5β1 and Enhances Its Trafficking in Migrating Pancreatic Carcinoma Cells

Human pancreatic ductal adenocarcinoma (PDAC) is characterized by early systemic dissemination. Although RhoC has been implicated in cancer cell migration, the relevant underlying molecular mechanisms remain unknown. RhoC has been implicated in the enhancement of cancer cell migration and invasion,...

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Main Authors: Li, Ningfeng Fiona, Gemenetzidis, Emilios, Marshall, Francis J., Davies, Derek, Yu, Yongwei, Frese, Kristopher, Froeling, Fieke E. M., Woolf, Adam K., Feakins, Roger M., Naito, Yoshiki, Iacobuzio-Donahue, Christine, Tuveson, David A., Hart, Ian R., Kocher, Hemant M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849283/
https://ncbi.nlm.nih.gov/pubmed/24312560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081575
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