In Vitro and In Vivo Evaluation of a (18)F-Labeled High Affinity NOTA Conjugated Bombesin Antagonist as a PET Ligand for GRPR-Targeted Tumor Imaging

Expression of the gastrin-releasing peptide receptor (GRPR) in prostate cancer suggests that this receptor can be used as a potential molecular target to visualize and treat these tumors. We have previously investigated an antagonist analog of bombesin (D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH(2), R...

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Detalhes bibliográficos
Main Authors: Varasteh, Zohreh, Åberg, Ola, Velikyan, Irina, Lindeberg, Gunnar, Sörensen, Jens, Larhed, Mats, Antoni, Gunnar, Sandström, Mattias, Tolmachev, Vladimir, Orlova, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849266/
https://ncbi.nlm.nih.gov/pubmed/24312607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081932
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