Downregulation of KPNA2 in non-small-cell lung cancer is associated with Oct4 expression

BACKGROUND: Oct4 is a major transcription factor related to stem cell self-renewal and differentiation. To fulfill its functions, it must be able to enter the nucleus and remain there to affect transcription. KPNA2, a member of the karyopherin family, plays a central role in nucleocytoplasmic transp...

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Autors principals: Li, Xiao-Lei, Jia, Lan-Ling, Shi, Mu-Mu, Li, Xin, Li, Zhong-Hua, Li, Hui-Feng, Wang, En-Hua, Jia, Xin-Shan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849263/
https://ncbi.nlm.nih.gov/pubmed/24070213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-232
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