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Respiratory uncoupling by increased H(+) or K(+) flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition
BACKGROUND: Ischemic preconditioning has been proposed to involve changes in mitochondrial H(+) and K(+) fluxes, in particular through activation of uncoupling proteins and ATP-sensitive K(+) channels (MitoK(ATP)). The objectives of the present study were to explore how increased H(+) and K(+) fluxe...
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Auteurs principaux: | , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2013
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3849260/ https://ncbi.nlm.nih.gov/pubmed/24053891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-14-40 |
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