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Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model

Mecp2 is a transcriptional repressor protein that is mutated in Rett syndrome, a neurodevelopmental disorder that is the second most common cause of mental retardation in women. It has been shown that the loss of the Mecp2 protein in Rett syndrome cells alters the transcriptional silencing of coding...

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Detalhes bibliográficos
Main Authors: Petazzi, Paolo, Sandoval, Juan, Szczesna, Karolina, Jorge, Olga C., Roa, Laura, Sayols, Sergi, Gomez, Antonio, Huertas, Dori, Esteller, Manel
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849168/
https://ncbi.nlm.nih.gov/pubmed/23611944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.24286
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