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Non-additive interactions between mitochondrial complex IV blockers and hypoxia in rat carotid body responses

The metabolic hypothesis of carotid body chemoreceptor hypoxia transduction proposes an impairment of ATP production as the signal for activation. We hypothesized that mitochondrial complex IV blockers and hypoxia would act synergistically in exciting afferent nerve activity. Following a pretreatmen...

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Detalhes bibliográficos
Main Authors: Donnelly, David F, Kim, Insook, Mulligan, Eileen M, Carroll, John L
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849127/
https://ncbi.nlm.nih.gov/pubmed/24096081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2013.09.009
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