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C→U Editing of Neurofibromatosis 1 mRNA Occurs in Tumors That Express Both the Type II Transcript and apobec-1, the Catalytic Subunit of the Apolipoprotein B mRNA–Editing Enzyme

C→U RNA editing of neurofibromatosis 1 (NF1) mRNA changes an arginine (CGA) to a UGA translational stop codon, predicted to result in translational termination of the edited mRNA. Previous studies demonstrated varying degrees of C→U RNA editing in peripheral nerve–sheath tumor samples (PNSTs) from p...

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Hlavní autoři: Mukhopadhyay, Debnath, Anant, Shrikant, Lee, Robert M., Kennedy, Susan, Viskochil, David, Davidson, Nicholas O.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC384902/
https://ncbi.nlm.nih.gov/pubmed/11727199
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