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C→U Editing of Neurofibromatosis 1 mRNA Occurs in Tumors That Express Both the Type II Transcript and apobec-1, the Catalytic Subunit of the Apolipoprotein B mRNA–Editing Enzyme

C→U RNA editing of neurofibromatosis 1 (NF1) mRNA changes an arginine (CGA) to a UGA translational stop codon, predicted to result in translational termination of the edited mRNA. Previous studies demonstrated varying degrees of C→U RNA editing in peripheral nerve–sheath tumor samples (PNSTs) from p...

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Udgivet i:Am J Hum Genet
Principais autores: Mukhopadhyay, Debnath, Anant, Shrikant, Lee, Robert M., Kennedy, Susan, Viskochil, David, Davidson, Nicholas O.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2001
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384902/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11727199/
https://ncbi.nlm.nih.govhttps://doi.org/10.1086/337952
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