TRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration

Tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4) is frequently overexpressed in carcinomas, suggesting a specific role in cancer. Although TRAF4 protein is predominantly found at tight junctions (TJs) in normal mammary epithelial cells (MECs), it accumulates in the cytoplasm of malig...

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Autores principales: Rousseau, Adrien, McEwen, Alastair G., Poussin-Courmontagne, Pierre, Rognan, Didier, Nominé, Yves, Rio, Marie-Christine, Tomasetto, Catherine, Alpy, Fabien
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848981/
https://ncbi.nlm.nih.gov/pubmed/24311986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001726
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