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Ferric iron chelation lowers brain iron levels after intracerebral hemorrhage in rats but does not improve outcome

Iron-mediated free radical damage contributes to secondary damage after intracerebral hemorrhage (ICH). Iron is released from heme after hemoglobin breakdown and accumulates in the parenchyma over days and then persists in the brain for months (e.g., hemosiderin). This non-heme iron has been linked...

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Detalhes bibliográficos
Main Authors: Auriat, Angela M., Silasi, Gergely, Wei, Zhouping, Paquette, Rosalie, Paterson, Phyllis, Nichol, Helen, Colbourne, Frederick
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848975/
https://ncbi.nlm.nih.gov/pubmed/22226595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.12.030
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