Metastatic colorectal cancer first-line treatment with bevacizumab: the impact of K-ras mutation

BACKGROUND: Bevacizumab plus chemotherapy prolongs progression-free survival (PFS) and overall survival (OS) in metastatic colorectal cancer (mCRC). Although there is strong evidence to suggest that the mutational status of the K-ras oncogene has a role as a predictive factor for activity in patient...

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Hlavní autoři: Rossi, Luigi, Veltri, Enzo, Zullo, Angelo, Zoratto, Federica, Colonna, Maria, Longo, Flavia, Mottolese, Marcella, Giannarelli, Diana, Ruco, Luigi, Marchetti, Paolo, Romiti, Adriana, Barucca, Viola, Giannini, Giuseppe, Bianchi, Loredana, Tomao, Silverio
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2013
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848929/
https://ncbi.nlm.nih.gov/pubmed/24348051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S43828
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