Down regulation of SPAG9 reduces growth and invasive potential of triple-negative breast cancer cells: possible implications in targeted therapy

BACKGROUND: Recently, we reported an association of a novel cancer testis (CT) antigen, sperm-associated antigen 9 (SPAG9) expression in breast cancer clinical samples, indicating its potential role in carcinogenesis. Around 15% breast cancers are designated as triple-negative for which treatment mo...

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Autors principals: Sinha, Abhilasha, Agarwal, Sumit, Parashar, Deepak, Verma, Archana, Saini, Shikha, Jagadish, Nirmala, Ansari, Abdul S, Lohiya, Nirmal K, Suri, Anil
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848771/
https://ncbi.nlm.nih.gov/pubmed/24330581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-69
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