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VEGF-A isoform modulation in an preclinical TNBS model of ulcerative colitis: protective effects of a VEGF164(b) therapy

BACKGROUND: Ulcerative colitis (UC) is the most common form of inflammatory bowel disease in the USA. A key component of UC is the increase in inflammatory angiogenesis of the colon during active disease. This increase is driven to a great extent by the over expression of VEGF-A. Recently, VEGF165(b...

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Détails bibliographiques
Auteurs principaux: Cromer, Walter E, Ganta, Chaitanya V, Patel, Mihir, Traylor, James, Kevil, Christopher G, Alexander, J Steven, Mathis, J Michael
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848761/
https://ncbi.nlm.nih.gov/pubmed/24020796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-207
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