Evaluation of DNA damage in COPD patients and its correlation with polymorphisms in repair genes

BACKGROUND: We investigated a potential link between genetic polymorphisms in genes XRCC1 (Arg399Gln), OGG1 (Ser326Cys), XRCC3 (Thr241Met), and XRCC4 (Ile401Thr) with the level of DNA damage and repair, accessed by comet and micronucleus test, in 51 COPD patients and 51 controls. METHODS: Peripheral...

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主要な著者: da Silva, Andréa Lúcia Gonçalves, da Rosa, Helen Tais, Karnopp, Thaís Evelyn, Charlier, Clara Forrer, Ellwanger, Joel Henrique, Moura, Dinara Jaqueline, Possuelo, Lia Gonçalves, Valim, Andréia Rosane de Moura, Guecheva, Temenouga Nikolova, Henriques, João Antonio Pêgas
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848611/
https://ncbi.nlm.nih.gov/pubmed/24053728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-93
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