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Increasing the α 2, 6 Sialylation of Glycoproteins May Contribute to Metastatic Spread and Therapeutic Resistance in Colorectal Cancer

Abnormal glycosylation due to dysregulated glycosyltransferases and glycosidases is a key phenomenon of many malignancies, including colorectal cancer (CRC). In particular, increased ST6 Gal I (β-galactoside α 2, 6 sialyltransferase) and subsequently elevated levels of cell-surface α 2, 6-linked sia...

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Detalhes bibliográficos
Main Authors: Park, Jung-Jin, Lee, Minyoung
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848550/
https://ncbi.nlm.nih.gov/pubmed/24312702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5009/gnl.2013.7.6.629
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