Expression of Heat Shock Protein 70 Modulates the Chemoresponsiveness of Pancreatic Cancer

BACKGROUND/AIMS: Heat shock protein (HSP) 70 is constitutively overexpressed in pancreatic cancer cells (PCCs) and appears to confer protection against chemotherapeutics. We investigated whether modulating HSP 70 increases chemoresponsiveness to gemcitabine in PCCs. METHODS: Varying concentrations o...

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Hlavní autoři: Hyun, Jong Jin, Lee, Hong Sik, Keum, Bora, Seo, Yeon Seok, Jeen, Yoon Tae, Chun, Hoon Jai, Um, Soon Ho, Kim, Chang Duck
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Gastroenterology; the Korean Society of Gastrointestinal Endoscopy; the Korean Association for the Study of the Liver; the Korean Society of Neurogastroenterology and Motility; Korean Association for the Study of Intestinal Diseases; Korean College of Helicobacter and Upper Gastrointestinal Research; Korean Pancreatobiliary Association; Korean Society of Gastrointestinal Cancer 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848545/
https://ncbi.nlm.nih.gov/pubmed/24312717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5009/gnl.2013.7.6.739
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