The whn transcription factor encoded by the nude locus contains an evolutionarily conserved and functionally indispensable activation domain.
Mutations in the whn gene are associated with the phenotype of congenital athymia and hairlessness in mouse and rat. The whn gene encodes a presumptive transcription factor with a DNA binding domain of the forkhead/ winged-helix class. Two previously described null alleles encode truncated whn prote...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1996
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790387/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9661 |
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