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One-Step Microfluidic Generation of Pre-Hatching Embryo-Like Core-Shell Microcapsules for Miniaturized 3D Culture of Pluripotent Stem Cells

A novel core-shell microcapsule system is developed in this study to mimic the miniaturized 3D architecture of pre-hatching embryos with an aqueous liquid core of embryonic cells and a hydrogel-shell of zona pellucida. This is done by microfabricating a non-planar microfluidic flow-focusing device t...

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Detalhes bibliográficos
Main Authors: Agarwal, Pranay, Zhao, Shuting, Bielecki, Peter, Rao, Wei, Choi, Jung K., Zhao, Yi, Yu, Jianhua, Zhang, Wujie, He, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848340/
https://ncbi.nlm.nih.gov/pubmed/24113543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3lc50678a
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