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Mitigation of Radiation Induced Pulmonary Vascular Injury by Delayed Treatment with Captopril

BACKGROUND AND OBJECTIVE: A single dose of 10 Gy radiation to the thorax of rats results in decreased total lung angiotensin-converting enzyme (ACE) activity, pulmonary artery distensibility and distal vascular density while increasing pulmonary vascular resistance (PVR) at 2-months post-exposure. I...

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Autores principales: MOLTHEN, Robert C., WU, Qingping, FISH, Brian L., MOULDER, John E., JACOBS, Elizabeth R., MEDHORA, Meetha M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848310/
https://ncbi.nlm.nih.gov/pubmed/22882664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1843.2012.02247.x
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